Are you interested in how viruses interact with host cells and interfere in their function? We are looking for a PhD candidate to participate in the multidisciplinary team of researchers, led by Dr Esther Nolte- t Hoen exploring the biology of extracellular vesicles (EVs) and their role in host-pathogen interactions.
EVs are vehicles for intercellular communication in several homeostatic and disease processes. Picornaviruses, which encompass a large family of viruses infecting humans and animals, exploit EV-mediated communication and have drastic effects on the number and molecular composition of EVs released by infected cells.
Moreover, picornaviruses can escape infected cells cloaked in EVs, which prevents binding by neutralizing antibodies. Within a team of researchers with expertise in cell biology, virology, and immunology you will contribute to elucidating mechanisms underlying the formation of picornavirus-induced EVs and their role in virus spreading and the antiviral immune response.
You will become a member of the Graduate School of Life Sciences in the PhD programme Infection and Immunity.
We offer a temporary position (1.0 FTE) for a period of one year. After a positive evaluation, the appointment will be extended with three years.
The gross salary starts with €2,443 per month in the first year and increases to €3,122 per month in the fourth year of employment (scale P according to the Collective Labour Agreement Dutch Universities) per month for a full-time employment.
Salaries are supplemented with a holiday bonus of 8% and a year-end bonus of 8.3% per year. In addition, Utrecht University offers excellent secondary conditions, including an attractive retirement scheme, (partly paid) parental leave and (multiple choice model).
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