The observation that patients receiving Radiotherapy (RT) show increased responses following Immunotherapy (IT) has boosted both fundamental and clinical RT / IT studies.
In the current project we will treat cancer patients with RT plus immune checkpoint immunotherapy. In parallel, pre-clinical mouse studies will be performed to optimize RT / IT treatment efficacy.
The clinical and preclinical studies will be combined with extensive molecular and immunological monitoring. The candidate will be involved in trial logistics and the pre-clinical mouse studies.
A combination of immunological (Flow, functional assays, Microscopy), molecular (RNA seq, qPCR) analysis of the human samples from the Radiotherapy / Immunotherapy (RT / IT) trial as well as the pre-clinical mouse samples are part of the activities.
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