Within this project the student will in vitro build an active network, using purified proteins.
A physicist’s first approximation of a biological cell would probably be a sphere of radius R with an elasticity of modulus E.
Whilst this approximation is about as correct as it is complete, it does address three crucial parameters of a cell : its shape, its size and its mechanical properties.
Biological processes like cell division and migration display a control over these parameters unprecedented by anything synthetic.
How does biology pull this off? Living materials are unique in the way they stay away from equilibrium : molecular motors, fueled by chemical energy, make otherwise static polymer networks alive’.
Within this project the student will in vitro build such an active network, using purified proteins. The goal is to understand the physics of these biological’ systems through a combination of rheology, confocal microscopy and image analysis.
You participate in a Bachelor or a Master study in physics, chemistry or biology. The internship must be a mandatory part of your curriculum.
You have a nationality of an EU-member state and / or you are a student at a Netherlands University. You must be available for at least 3 months, although longer is preferable.
Terms of employment
At the start of the traineeship your trainee plan will be set out, in consultation with your AMOLF supervisor.