Postdoc position: Cell type specific function in visual cortex during multisensory processing
Vrije Universiteit Amsterdam
Amsterdam De Boelelaan
2 dagen geleden

The In Vivo Neurophysiology team is looking for a postdoc for a 3-year project that will be carried out at the Integrative Neurophysiology (INF) division at the Center for Neurogenomics and Cognitive Research (CNCR) at the VU Amsterdam (chair prof.dr. Huib Mansvelder).

See, touch, feel! How does our brain combine different senses?

Our brain has specialized regions to encode information from our five main senses. To experience the world around us, senses need to be combined, but we do not yet understand how our brain performs this function.

We will test the hypothesis that the cerebral cortex combines information already in areas specialized for a single sense.

We will record brain activity in behaving animals performing a combined touch-vision task to understand how multisensory information is coded.

Detailed understanding of the mechanisms operating at the level of cells and brain systems can provide clues to develop therapeutic treatments after brain damage.

As postdoc in the in vivo neurophysiology team, your research will aim to elucidate cell-type specific function in primary visual cortex underlying the emergence of multi-sensory integration and sensory-guided decision-making.

This postdoc project is funded through a collaborative grant from NWO (ENW-M-2), which involves a synergistic collaboration with prof.

Cyriel Pennartz from the University of Amsterdam and a 2nd postdoc position at UvA-SILS. The VU position will focus on disentangling the cellular substrates during multisensory processing, whereas the postdoc position at the UvA will elucidate the contribution of ensembles of neurons to the same standardized behavioral task.

We envision surplus value by constantly aligning the 2 postdoc projects through regular meetings (see also ).

The INF department and CNCR institute are the home of several groups at the frontier of studying the link between brain circuitry and well-defined rodent behavior.

The postdoc project will be fully integrated with ongoing research and the postdoc candidate will experience a jump-start because necessary techniques and expertise are readily available within the project and associated research teams.

Your duties

  • You will use a repertoire of state-of-the-art approaches in circuit neuroscience such as single unit and population electrophysiology in anaesthetized and behaving mice, opto- or chemogenetics and histology
  • You will have the opportunity to supervise Bachelor’s and Master’s students
  • Work in close collaboration with the UvA postdoc and group
  • Requirements

  • We are looking for candidates with a PhD in Neuroscience and a strong motivation to pursue a career in science. This translates to a finished PhD thesis (or submitted to the assessment committee) with one or more first-author data manuscripts published in peer-reviewed journals or submitted.
  • Candidates without a PhD or without published / accepted manuscript(s) will not be considered

  • Prior experience with single unit electrophysiology (silicon probes, Neuropixels, cluster analysis, patch clamp or loose patch electrophysiology) and surgical techniques is essential
  • Experience with spike data analysis and knowledge of a programming language (Matlab, Python) is preferred
  • A permit to work with animals is preferred
  • What are we offering?

    A challenging position in a socially involved organization and multidisciplinary department. INF / CNCR hosts research group focusing on research questions that range from curiosity driving to bench-to-bedside research (cncr.

    nl). You will be part of a collaborative, enthusiastic team consisting of multiple PhD-students and experienced post-docs with diverse cultural backgrounds in which we collectively work on important research questions, using experimental approaches.

    The salary will be in accordance with university regulations for academic personnel and amounts €3561 (scale 10.5) - €4490 (10.

    12) per month depending on previous research experience, based on a full-time employment. The job profile : is based on the university job ranking system and is vacant for at least 1 FTE.

    The appointment will initially be for 1 year. After a satisfactory evaluation of the initial appointment, the contract will be extended for a total duration of 3 years.

    Additionally, the VU Amsterdam offers excellent fringe benefits and various schemes and regulations to promote a good work / life balance, such as :

  • 8% holiday allowance and 8.3% end-of-year bonus
  • contribution to commuting expenses
  • optional model for designing a personalized benefits package
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